News

“Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities.”

Garrett, M., J. Sperry, D. Braas, W. Yan, T. M. Le, J. Mottahedeh, K. Ludwig, A. Eskin, Y. Qin, R. Levy, J. J. Breunig, F. Pajonk, T. G. Graeber, C. G. Radu, H. Christofk, R. M. Prins, A. Lai, L. M. Liau, G. Coppola and H. I. Kornblum
Cancer Metab
, 2018.

“Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.”

Haney, M. S., C. J. Bohlen, D. W. Morgens, J. A. Ousey, A. A. Barkal, C. K. Tsui, B. K. Ego, R. Levin, R. A. Kamber, H. Collins, A. Tucker, A. Li, D. Vorselen, L. Labitigan, E. Crane, E. Boyle, L. Jiang, J. Chan, E. Rincon, W. J. Greenleaf, B. Li, M. P. Snyder, I. L. Weissman, J. A. Theriot, S. R. Collins, B. A. Barres and M. C. Bassik
Nat Genet
, 2018.

“Diltiazem Promotes Regenerative Axon Growth.”

Huebner, E. A., S. Budel, Z. Jiang, T. Omura, T. S. Ho, L. Barrett, J. S. Merkel, L. M. Pereira, N. A. Andrews, X. Wang, B. Singh, K. Kapur, M. Costigan, S. M. Strittmatter and C. J. Woolf
Mol Neurobiol
, 2018.

“N-acetylcysteine targets 5 lipoxygenase-derived, toxic lipids and can synergize with PGE2 to inhibit ferroptosis and improve outcomes following hemorrhagic stroke in mice.”

Karuppagounder, S. S., L. Alin, Y. Chen, D. Brand, M. W. Bourassa, K. Dietrich, C. M. Wilkinson, C. A. Nadeau, A. Kumar, S. Perry, J. T. Pinto, V. Darley-Usmar, S. Sanchez, G. L. Milne, D. Pratico, T. R. Holman, S. T. Carmichael, G. Coppola, F. Colbourne and R. R. Ratan
Ann Neurol
, 2018.

“The interferon response as a common final pathway for many preconditioning stimuli: unexpected crosstalk between hypoxic adaptation and antiviral defense.”

Karuppagounder, S. S., Y. Zhai, Y. Chen, R. He and R. R. Ratan
Cond Med
, 2018.

“Schwann cell O-GlcNAcylation promotes peripheral nerve remyelination via attenuation of the AP-1 transcription factor JUN.”

Kim, S., J. C. Maynard, A. Strickland, A. L. Burlingame and J. Milbrandt
Proc Natl Acad Sci U S A
, 2018.

“Omics approaches for subcellular translation studies.”

Koppel, I. and M. Fainzilber
Mol Omics
, 2018.

“Generation and post-injury integration of human spinal cord neural stem cells.”

Kumamaru, H., K. Kadoya, A. F. Adler, Y. Takashima, L. Graham, G. Coppola and M. H. Tuszynski
Nat Methods
, 2018.

“Activation of Intrinsic Growth State Enhances Host Axonal Regeneration into Neural Progenitor Cell Grafts.”

Kumamaru, H., P. Lu, E. S. Rosenzweig and M. H. Tuszynski
Stem Cell Reports
, 2018.

“Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration.”

Latremoliere, A., L. Cheng, M. DeLisle, C. Wu, S. Chew, E. B. Hutchinson, A. Sheridan, C. Alexandre, F. Latremoliere, S. H. Sheu, S. Golidy, T. Omura, E. A. Huebner, Y. Fan, M. C. Whitman, E. Nguyen, C. Hermawan, C. Pierpaoli, M. A. Tischfield, C. J. Woolf and E. C. Engle
Cell Rep
, 2018.

“Increased Single-Fiber Jitter Level Is Associated With Reduction in Motor Function With Aging.”

Chung, T., Y. Tian, J. Walston and A. Hoke
Am J Phys Med Rehabil
, 2018.

“Mechanistic Differences in Neuropathic Pain Modalities Revealed by Correlating Behavior with Global Expression Profiling.”

Cobos, E. J., C. A. Nickerson, F. Gao, V. Chandran, I. Bravo-Caparros, R. Gonzalez-Cano, P. Riva, N. A. Andrews, A. Latremoliere, C. R. Seehus, G. Perazzoli, F. R. Nieto, N. Joller, M. W. Painter, C. H. E. Ma, T. Omura, E. J. Chesler, D. H. geschwind, G. Coppola, M. Rangachari, C. J. Woolf and M. Costigan
Cell Rep
, 2018.

“Wearable Sensors to Monitor, Enable Feedback, and Measure Outcomes of Activity and Practice.”

Dobkin, B. H. and C. Martinez
Curr Neurol Neurosci Rep
, 2018.

“Injured adult motor and sensory axons regenerate into appropriate organotypic domains of neural progenitor grafts.”

Dulin, J. N., A. F. Adler, H. Kumamaru, G. H. D. Poplawski, C. Lee-Kubli, H. Strobl, D. Gibbs, K. Kadoya, J. W. Fawcett, P. Lu and M. H. Tuszynski
Nat Commun
, 2018.

“Revealing nascent proteomics in signaling pathways and cell differentiation.”

Forester, C. M., Q. Zhao, N. J. Phillips, A. Urisman, R. J. Chalkley, J. A. Oses-Prieto, L. Zhang, D. Ruggero and A. L. Burlingame
Proc Natl Acad Sci U S A
, 2018.

“Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington’s Disease Knock-In Mouse Models.”

Franich, N. R., M. Basso, E. A. Andre, J. Ochaba, A. Kumar, S. Thein, G. Fote, M. Kachemov, A. L. Lau, S. Y. Yeung, A. Osmand, S. O. Zeitlin, R. R. Ratan, L. M. Thompson and J. S. Steffan
J Huntingtons Dis
, 2018.