News - Page 11 of 40

“LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer.”

Sas-Chen, A., M. R. Aure, L. Leibovich, S. Carvalho, Y. Enuka, C. Korner, M. Polycarpou-Schwarz, S. Lavi, N. Nevo, Y. Kuznetsov, J. Yuan, F. Azuaje, F. A. M. G. C. K. K. Oslo Breast Cancer Research Consortium SauerTorillGeislerJurgenHofvindSolveigBathenTone, I. Ulitsky, S. Diederichs, S. Wiemann, Z. Yakhini, V. N. Kristensen, A. L. Borresen-Dale and Y. Yarden
EMBO Mol Med, 2016.

“Regulatory module involving FGF13, miR-504, and p53 regulates ribosomal biogenesis and supports cancer cell survival.”

Bublik, D. R., S. Bursac, M. Sheffer, I. Orsolic, T. Shalit, O. Tarcic, E. Kotler, O. Mouhadeb, Y. Hoffman, G. Fuchs, Y. Levin, S. Volarevic and M. Oren
Proc Natl Acad Sci U S A, 2016.

“Interfering with the Dimerization of the ErbB Receptors by Transmembrane Domain-Derived Peptides Inhibits Tumorigenic Growth in Vitro and in Vivo.”

Bublil, E. M., T. Cohen, C. J. Arnusch, A. Peleg, G. Pines, S. Lavi, Y. Yarden and Y. Shai
Biochemistry, 2016.

“Immunotherapy of cancer: from monoclonal to oligoclonal cocktails of anti-cancer antibodies: IUPHAR Review X.”

Carvalho, S., F. Levi-Schaffer, M. Sela and Y. Yarden
Br J Pharmacol, 2016.

“Modulation of SQSTM1/p62 activity by N-terminal arginylation of the endoplasmic reticulum chaperone HSPA5/GRP78/BiP.”

Cha-Molstad, H., J. E. Yu, S. H. Lee, J. G. Kim, K. S. Sung, J. Hwang, Y. D. Yoo, Y. J. Lee, S. T. Kim, D. H. Lee, A. Ciechanover, B. Y. Kim and Y. T. Kwon
Autophagy, 2016.

“p62- and ubiquitin-dependent stress-induced autophagy of the mammalian 26S proteasome.”

Cohen-Kaplan, V., I. Livneh, N. Avni, B. Fabre, T. Ziv, Y. T. Kwon and A. Ciechanover
SOURCEProc Natl Acad Sci U S A, 2016.

“MicroRNAs: Non-coding fine tuners of receptor tyrosine kinase signalling in cancer.”

Donzelli, S., M. Cioce, P. Muti, S. Strano, Y. Yarden and G. Blandino
Semin Cell Dev Biol, 2016.

“Post-translational modification profiling – A novel tool for mapping the protein modification landscape in cancer.”

Eisenberg-Lerner, A., A. Ciechanover and Y. Merbl
Exp Biol Med (Maywood), 2016.

“The testis-specific USP26 is a deubiquitinating enzyme of the ubiquitin ligase Mdm2.”

Lahav-Baratz, S., Y. Kravtsova-Ivantsiv, S. Golan and A. Ciechanover
Biochem Biophys Res Commun, 2016.

“Inflammatory networks underlying colorectal cancer.”

Lasry, A., A. Zinger and Y. Ben-Neriah
Nat Immunol, 2016.

“The Paradox of p53: What, How, and Why?”

Aylon, Y. and M. Oren
Cold Spring Harb Perspect Med, 2016.

“Genome instability: Linking ageing and brain degeneration.”

Barzilai, A., B. Schumacher and Y. Shiloh
Mech Ageing Dev, 2016.

“Numerous proteins with unique characteristics are degraded by the 26S proteasome following monoubiquitination.”

Braten, O., I. Livneh, T. Ziv, A. Admon, I. Kehat, L. H. Caspi, H. Gonen, B. Bercovich, A. Godzik, S. Jahandideh, L. Jaroszewski, T. Sommer, Y. T. Kwon, M. Guharoy, P. Tompa and A. Ciechanover
Proc Natl Acad Sci U S A, 2016.

“A PAX3/BRN2 rheostat controls the dynamics of BRAF mediated MITF regulation in MITF(high) /AXL(low) melanoma.”

Smith, M. P., S. Rana, J. Ferguson, E. J. Rowling, K. T. Flaherty, J. A. Wargo, R. Marais and C. Wellbrock
Pigment Cell Melanoma Res, 2019.

“Genome-wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy.”

Sahu, A. D., S. L. J, Z. Wang, G. Zhang, R. Iglesias-Bartolome, T. Tian, Z. Wei, B. Miao, N. U. Nair, O. Ponomarova, A. A. Friedman, A. Amzallag, T. Moll, G. Kasumova, P. Greninger, R. K. Egan, L. J. Damon, D. T. Frederick, L. Jerby-Arnon, A. Wagner, K. Cheng, S. G. Park, W. Robinson, K. Gardner, G. Boland, S. Hannenhalli, M. Herlyn, C. Benes, K. Flaherty, J. Luo, J. S. Gutkind and E. Ruppin
Mol Syst Biol, 2019.

“A Novel Mitochondrial Inhibitor Blocks MAPK Pathway and Overcomes MAPK Inhibitor Resistance in Melanoma.”

Vashisht Gopal, Y. N., S. Gammon, R. Prasad, B. Knighton, F. Pisaneschi, J. Roszik, N. Feng, S. Johnson, S. Pramanik, J. Sudderth, D. Sui, C. Hudgens, G. M. Fischer, W. Deng, A. Reuben, W. Peng, J. Wang, J. L. McQuade, M. T. Tetzlaff, M. E. Di Francesco, J. Marszalek, D. Piwnica-Worms, R. J. DeBerardinis and M. A. Davies
Clin Cancer Res, 2019.