News - Page 12 of 40

“PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1(+)CD38(hi) cells and anti-PD-1 resistance.”

Verma, V., R. K. Shrimali, S. Ahmad, W. Dai, H. Wang, S. Lu, R. Nandre, P. Gaur, J. Lopez, M. Sade-Feldman, K. Yizhak, S. L. Bjorgaard, K. T. Flaherty, J. A. Wargo, G. M. Boland, R. J. Sullivan, G. Getz, S. A. Hammond, M. Tan, J. Qi, P. Wong, T. Merghoub, J. Wolchok, N. Hacohen, J. E. Janik, M. Mkrtichyan, S. Gupta and S. N. Khleif
Nat Immunol, 2019.

“Salt-Inducible Kinases: Physiology, Regulation by cAMP, and Therapeutic Potential: (Trends Endocrinol. Metab. 29, 723-735, 2018).”

Wein, M. N., M. Foretz, D. E. Fisher, R. J. Xavier and H. M. Kronenberg
Trends Endocrinol Metab, 2019.

“A Melanoma Patient-Derived Xenograft Model.”

Xiao, M., V. W. Rebecca and M. Herlyn
J Vis Exp, 2019.

“The LATS2 tumor suppressor inhibits SREBP and suppresses hepatic cholesterol accumulation.”

Aylon, Y., A. Gershoni, R. Rotkopf, I. E. Biton, Z. Porat, A. P. Koh, X. Sun, Y. Lee, M. I. Fiel, Y. Hoshida, S. L. Friedman, R. L. Johnson and M. Oren
Genes Dev, 2016.

“Widespread parainflammation in human cancer.”

Aran, D., A. Lasry, A. Zinger, M. Biton, E. Pikarsky, A. Hellman, A. J. Butte and Y. Ben-Neriah
Genome Biol, 2016.

“B cells sustain inflammation and predict response to immune checkpoint blockade in human melanoma.”

Griss, J., W. Bauer, C. Wagner, M. Simon, M. Chen, K. Grabmeier-Pfistershammer, M. Maurer-Granofszky, F. Roka, T. Penz, C. Bock, G. Zhang, M. Herlyn, K. Glatz, H. Laubli, K. D. Mertz, P. Petzelbauer, T. Wiesner, M. Hartl, W. F. Pickl, R. Somasundaram, P. Steinberger and S. N. Wagner
Nat Commun, 2019.

“CADM1 is a TWIST1-regulated suppressor of invasion and survival.”

Hartsough, E. J., M. B. Weiss, S. A. Heilman, T. J. Purwin, C. H. Kugel, 3rd, S. R. Rosenbaum, D. A. Erkes, M. Tiago, K. HooKim, I. Chervoneva and A. E. Aplin
Cell Death Dis, 2019.

“Local genomic features predict the distinct and overlapping binding patterns of the bHLH-Zip family oncoproteins MITF and MYC-MAX.”

Hejna, M., W. M. Moon, J. Cheng, A. Kawakami, D. E. Fisher and J. S. Song
Pigment Cell Melanoma Res, 2019.

“Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility.”

Kaur, A., B. L. Ecker, S. M. Douglass, C. H. Kugel, 3rd, M. R. Webster, F. V. Almeida, R. Somasundaram, J. Hayden, E. Ban, H. Ahmadzadeh, J. Franco-Barraza, N. Shah, I. A. Mellis, F. Keeney, A. Kossenkov, H. Y. Tang, X. Yin, Q. Liu, X. Xu, M. Fane, P. Brafford, M. Herlyn, D. W. Speicher, J. A. Wargo, M. T. Tetzlaff, L. E. Haydu, A. Raj, V. Shenoy, E. Cukierman and A. T. Weeraratna
Cancer Discov, 2019.

“Effects of Oncogenic Galphaq and Galpha11 Inhibition by FR900359 in Uveal Melanoma.”

Lapadula, D., E. Farias, C. E. Randolph, T. J. Purwin, D. McGrath, T. H. Charpentier, L. Zhang, S. Wu, M. Terai, T. Sato, G. G. Tall, N. Zhou, P. B. Wedegaertner, A. E. Aplin, J. Aguirre-Ghiso and J. L. Benovic
Mol Cancer Res, 2019.

“Sun exposure and protection practices in children after allogeneic hematopoietic stem cell transplantation: A Survey-Based Cross-Sectional Cohort Study.”

Li, E. B., J. S. Song, J. T. Huang, E. B. Hawryluk, W. B. London, D. Guo, M. Sridharan, D. E. Fisher, C. J. Rea, L. E. Lehmann and C. N. Duncan
Pediatr Dermatol, 2019.

“Tyrosine Kinase Inhibitor and Immune Checkpoint Inhibitor Responses in KIT-Mutant Metastatic Melanoma.”

McKean, M., J. Oba, J. Ma, K. G. Roth, W. L. Wang, M. P. Macedo, F. C. L. Carapeto, L. E. Haydu, A. E. Siroy, P. Vo, D. S. Hong, A. K. Eterovic, K. P. Patel, R. L. Bassett, Jr., E. A. Grimm, A. J. Lazar and S. E. Woodman
J Invest Dermatol, 2019.

“The challenge of classifying metastatic cell properties by molecular profiling exemplified with cutaneous melanoma cells and their cerebral metastasis from patient derived mouse xenografts.”

Neuditschko, B., L. Janker, L. Niederstaetter, J. Brunmair, K. Krivanek, S. Izraely, O. Sagi-Assif, T. Meshel, B. Keppler, G. Del Favero, I. P. Witz and C. Gerner
Mol Cell Proteomics, 2019.

“C57BL/6 congenic mouse NRAS(Q61K) melanoma cell lines are highly sensitive to the combination of Mek and Akt inhibitors in vitro and in vivo.”

Petit, V., J. Raymond, C. Alberti, M. Pouteaux, S. J. Gallagher, M. Q. Nguyen, A. E. Aplin, V. Delmas and L. Larue
Pigment Cell Melanoma Res, 2019.

“The next-generation BET inhibitor, PLX51107, delays melanoma growth in a CD8-mediated manner.”

Erkes, D. A., C. O. Field, C. Capparelli, M. Tiago, T. J. Purwin, I. Chervoneva, A. C. Berger, E. J. Hartsough, J. Villanueva and A. E. Aplin
Pigment Cell Melanoma Res, 2019.

“STING Signaling in Melanoma Cells Shapes Antigenicity and Can Promote Antitumor T-cell Activity.”

Falahat, R., P. Perez-Villarroel, A. W. Mailloux, G. Zhu, S. Pilon-Thomas, G. N. Barber and J. J. Mule
Cancer Immunol Res, 2019.