News

“Liquid biopsy utility for the surveillance of cutaneous malignant melanoma patients.”

Huang, S. K. and D. S. Hoon
Mol Oncol
, 2016.

“Clinicopathological features and clinical outcomes associated with TP53 and BRAFNon-V600 mutations in cutaneous melanoma patients.”

Kim, D. W., L. E. Haydu, A. Y. Joon, R. L. Bassett, Jr., A. E. Siroy, M. T. Tetzlaff, M. J. Routbort, R. N. Amaria, J. A. Wargo, J. L. McQuade, J. Kemnade, P. Hwu, S. E. Woodman, J. Roszik, K. B. Kim, J. E. Gershenwald, A. J. Lazar and M. A. Davies
Cancer
, 2016.

“Targeting Notch enhances the efficacy of ERK inhibitors in BRAF-V600E melanoma.”

Krepler, C., M. Xiao, M. Samanta, A. Vultur, H. Y. Chen, P. Brafford, P. I. Reyes-Uribe, M. Halloran, T. Chen, X. He, D. Hristova, Q. Liu, A. A. Samatar, M. A. Davies, K. L. Nathanson, M. Fukunaga-Kalabis, M. Herlyn and J. Villanueva
Oncotarget
, 2016.

“Personalized Preclinical Trials in BRAF Inhibitor-Resistant Patient-Derived Xenograft Models Identify Second-Line Combination Therapies.”

Krepler, C., M. Xiao, K. Sproesser, P. A. Brafford, B. Shannan, M. Beqiri, Q. Liu, W. Xu, B. Garman, K. L. Nathanson, X. Xu, G. C. Karakousis, G. B. Mills, Y. Lu, T. A. Ahmed, P. I. Poulikakos, G. Caponigro, M. Boehm, M. Peters, L. M. Schuchter, A. T. Weeraratna and M. Herlyn
Clin Cancer Res
, 2016.

“MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells.”

Kryukov, G. V., F. H. Wilson, J. R. Ruth, J. Paulk, A. Tsherniak, S. E. Marlow, F. Vazquez, B. A. Weir, M. E. Fitzgerald, M. Tanaka, C. M. Bielski, J. M. Scott, C. Dennis, G. S. Cowley, J. S. Boehm, D. E. Root, T. R. Golub, C. B. Clish, J. E. Bradner, W. C. Hahn and L. A. Garraway
Science
, 2016.

“Adjuvant Autologous Melanoma Vaccine for Macroscopic Stage III Disease: Survival, Biomarkers, and Improved Response to CTLA-4 Blockade.”

Lotem, M., S. Merims, S. Frank, T. Hamburger, A. Nissan, L. Kadouri, J. Cohen, R. Straussman, G. Eisenberg, S. Frankenburg, E. Carmon, B. Alaiyan, S. Shneibaum, Z. Ozge Ayyildiz, M. Isbilen, K. Mert Senses, I. Ron, H. Steinberg, Y. Smith, E. Shiloni, A. O. Gure and T. Peretz
J Immunol Res
, 2016.

“Clinical, Molecular, and Immune Analysis of Dabrafenib-Trametinib Combination Treatment for BRAF Inhibitor-Refractory Metastatic Melanoma: A Phase 2 Clinical Trial.”

Chen, G., J. L. McQuade, D. J. Panka, C. W. Hudgens, A. Amin-Mansour, X. J. Mu, S. Bahl, J. Jane-Valbuena, K. M. Wani, A. Reuben, C. A. Creasy, H. Jiang, Z. A. Cooper, J. Roszik, R. L. Bassett, Jr., A. Y. Joon, L. M. Simpson, R. D. Mouton, I. C. Glitza, S. P. Patel, W. J. Hwu, R. N. Amaria, A. Diab, P. Hwu, A. J. Lazar, J. A. Wargo, L. A. Garraway, M. T. Tetzlaff, R. J. Sullivan, K. B. Kim and M. A. Davies
JAMA Oncol
, 2016.

“Inflammatory Marker Testing Identifies CD74 Expression in Melanoma Tumor Cells, and its Expression Associates with Favorable Survival for Stage III Melanoma.”

Ekmekcioglu, S., M. A. Davies, K. Tanese, J. Roszik, M. Shin-Sim, R. L. Bassett, Jr., D. R. Milton, S. E. Woodman, V. G. Prieto, J. E. Gershenwald, D. L. Morton, D. S. Hoon and E. A. Grimm
Clin Cancer Res
, 2016.

“Immune Monitoring of Patients Treated With a Whole-Cell Melanoma Vaccine Engineered to Express 4-1BBL.”

Engelstein, R., S. Merims, G. Eisenberg, J. Cohen, S. Frank, T. Hamburger, S. Frankenburg, I. Ron, R. Isacson, T. Grenader, H. Steinberg, C. J. Cohen, T. Peretz and M. Lotem
J Immunother
, 2016.

“Mechanisms of node of Ranvier assembly.”

Rasband, M. N. and E. Peles
Nat Rev Neurosci
, 2021.

“Epigenetic regulators of neuronal ferroptosis identify novel therapeutics for neurological diseases: HDACs, transglutaminases, and HIF prolyl hydroxylases.”

Rroji, O., A. Kumar, S. S. Karuppagounder and R. R. Ratan
Neurobiol Dis
, 2021.

“Non-Cell-Autonomous Regulation of Optic Nerve Regeneration by Amacrine Cells.”

Sergeeva, E. G., P. A. Rosenberg and L. I. Benowitz
Front Cell Neurosci
, 2021.

“Ankyrin-R regulates fast-spiking interneuron excitability through perineuronal nets and Kv3.1b K(+) channels.”

Stevens, S. R., C. M. Longley, Y. Ogawa, L. H. Teliska, A. S. Arumanayagam, S. Nair, J. A. Oses-Prieto, A. L. Burlingame, M. D. Cykowski, M. Xue and M. N. Rasband
Elife
, 2021.

“Differential Contribution of Cadm1-Cadm3 Cell Adhesion Molecules to Peripheral Myelinated Axons.”

Sukhanov, N., A. Vainshtein, Y. Eshed-Eisenbach and E. Peles
J Neurosci
, 2021.

“Chemokine CCL5 promotes robust optic nerve regeneration and mediates many of the effects of CNTF gene therapy.”

Xie, L., Y. Yin and L. Benowitz
Proc Natl Acad Sci U S A
, 2021.

“Uveal melanoma: From diagnosis to treatment and the science in between.”

Chattopadhyay, C., D. W. Kim, D. S. Gombos, J. Oba, Y. Qin, M. D. Williams, B. Esmaeli, E. A. Grimm, J. A. Wargo, S. E. Woodman and S. P. Patel
Cancer
, 2016.