News

“Niche stiffness underlies the ageing of central nervous system progenitor cells.”

Segel, M., B. Neumann, M. F. E. Hill, I. P. Weber, C. Viscomi, C. Zhao, A. Young, C. C. Agley, A. J. Thompson, G. A. Gonzalez, A. Sharma, S. Holmqvist, D. H. Rowitch, K. Franze, R. J. M. Franklin and K. J. Chalut
Nature
, 2019.

“Myelin in the Central Nervous System: Structure, Function, and Pathology.”

Stadelmann, C., S. Timmler, A. Barrantes-Freer and M. Simons
Physiol Rev
, 2019.

“Grey matter myelination.”

Timmler, S. and M. Simons
Nature
, 2019.

“Oligodendrocytes Support Neuronal Glutamatergic Transmission via Expression of Glutamine Synthetase.”

Xin, W., Y. A. Mironova, H. Shen, R. A. M. Marino, A. Waisman, W. H. Lamers, D. E. Bergles and A. Bonc
Cell Rep
, 2019.

“Changes in the Oligodendrocyte Progenitor Cell Proteome with Ageing.”

de la Fuente, A. G., R. M. L. Queiroz, T. Ghosh, C. E. McMurran, J. F. Cubillos, D. E. Bergles, D. C. Fitzgerald, C. A. Jones, K. S. Lilley, C. P. Glover and R. J. M. Franklin
Mol Cell Proteomics
, 2020.

“Immune cell modulation of oligodendrocyte lineage cells.”

Harrington, E. P., D. E. Bergles and P. A. Calabresi
Neurosci Lett
, 2020.

“Exploiting Allosteric Properties of RAF and MEK Inhibitors to Target Therapy-Resistant Tumors Driven by Oncogenic BRAF Signaling.”

Adamopoulos, C., T. A. Ahmed, M. R. Tucker, P. M. U. Ung, M. Xiao, Z. Karoulia, A. Amabile, X. Wu, S. A. Aaronson, C. Ang, V. W. Rebecca, B. D. Brown, A. Schlessinger, M. Herlyn, Q. Wang, D. E. Shaw and P. I. Poulikakos
Cancer Discov
, 2021.

“Enhancing Oligodendrocyte Myelination Rescues Synaptic Loss and Improves Functional Recovery after Chronic Hypoxia.”

Wang, F., Y. J. Yang, N. Yang, X. J. Chen, N. X. Huang, J. Zhang, Y. Wu, Z. Liu, X. Gao, T. Li, G. Q. Pan, S. B. Liu, H. L. Li, S. P. J. Fancy, L. Xiao, J. R. Chan and F. Mei
Neuron
, 2018.

“Transforming growth factor-beta renders ageing microglia inhibitory to oligodendrocyte generation by CNS progenitors.”

Baror, R., B. Neumann, M. Segel, K. J. Chalut, S. P. J. Fancy, D. P. Schafer and R. J. M. Franklin
Glia
, 2019.

“Sephin1, which prolongs the integrated stress response, is a promising therapeutic for multiple sclerosis.”

Chen, Y., J. R. Podojil, R. B. Kunjamma, J. Jones, M. Weiner, W. Lin, S. D. Miller and B. Popko
Brain
, 2019.

“Two adhesive systems cooperatively regulate axon ensheathment and myelin growth in the CNS.”

Djannatian, M., S. Timmler, M. Arends, M. Luckner, M. T. Weil, I. Alexopoulos, N. Snaidero, B. Schmid, T. Misgeld, W. Mobius, M. Schifferer, E. Peles and M. Simons
Nat Commun
, 2019.

“The UPR-PERK pathway is not a promising therapeutic target for mutant SOD1-induced ALS.”

Dzhashiashvili, Y., C. P. Monckton, H. S. Shah, R. B. Kunjamma and B. Popko
Neurobiol Dis
, 2019.

“Molecular Control of Oligodendrocyte Development.”

Elbaz, B. and B. Popko
Trends Neurosci
, 2019.

“Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling.”

Gunner, G., L. Cheadle, K. M. Johnson, P. Ayata, A. Badimon, E. Mondo, M. A. Nagy, L. Liu, S. M. Bemiller, K. W. Kim, S. A. Lira, B. T. Lamb, A. R. Tapper, R. M. Ransohoff, M. E. Greenberg, A. Schaefer and D. P. Schafer
Nat Neurosci
, 2019.

“Oligodendrocyte precursor cells present antigen and are cytotoxic targets in inflammatory demyelination.”

Kirby, L., J. Jin, J. G. Cardona, M. D. Smith, K. A. Martin, J. Wang, H. Strasburger, L. Herbst, M. Alexis, J. Karnell, T. Davidson, R. Dutta, J. Goverman, D. Bergles and P. A. Calabresi
Nat Commun
, 2019.

“Potential role of iron in repair of inflammatory demyelinating lesions.”

Lee, N. J., S. K. Ha, P. Sati, M. Absinta, G. Nair, N. J. Luciano, E. C. Leibovitch, C. C. Yen, T. A. Rouault, A. C. Silva, S. Jacobson and D. S. Reich
J Clin Invest
, 2019.