“Proteasome ubiquitin receptor PSMD4 is an amplification target in breast cancer and may predict sensitivity to PARPi.”
Fejzo, M. S., L. Anderson, H. W. Chen, E. Guandique, O. Kalous, D. Conklin and D. J. SlamonGenes Chromosomes Cancer, 2017.
Genes Chromosomes Cancer, 2017.
“A patient-derived-xenograft platform to study BRCA-deficient ovarian cancers.”
George, E., H. Kim, C. Krepler, B. Wenz, M. Makvandi, J. L. Tanyi, E. Brown, R. Zhang, P. Brafford, S. Jean, R. H. Mach, Y. Lu, G. B. Mills, M. Herlyn, M. Morgan, X. Zhang, R. Soslow, R. Drapkin, N. Johnson, Y. Zheng, G. Cotsarelis, K. L. Nathanson and F. SimpkinsJCI Insight, 2017.
“Efficacy and safety of trabectedin or dacarbazine in patients with advanced uterine leiomyosarcoma after failure of anthracycline-based chemotherapy: Subgroup analysis of a phase 3, randomized clinical trial.”
Hensley, M. L., S. R. Patel, M. von Mehren, K. Ganjoo, R. L. Jones, A. Staddon, D. Rushing, M. Milhem, B. Monk, G. Wang, S. McCarthy, R. E. Knoblauch, T. V. Parekh, R. G. Maki and G. D. DemetriGynecol Oncol, 2017.
“High grade serous ovarian carcinomas originate in the fallopian tube.”
Labidi-Galy, S. I., E. Papp, D. Hallberg, N. Niknafs, V. Adleff, M. Noe, R. Bhattacharya, M. Novak, S. Jones, J. Phallen, C. A. Hruban, M. S. Hirsch, D. I. Lin, L. Schwartz, C. L. Maire, J. C. Tille, M. Bowden, A. Ayhan, L. D. Wood, R. B. Scharpf, R. Kurman, T. L. Wang, I. M. Shih, R. Karchin, R. Drapkin and V. E. VelculescuNat Commun, 2017.
“It’s Totally Tubular…Riding The New Wave of Ovarian Cancer Research.”
Perets, R. and R. DrapkinCancer Res, 2016.
“CCNE1 amplification and centrosome number abnormality in serous tubal intraepithelial carcinoma: further evidence supporting its role as a precursor of ovarian high-grade serous carcinoma.”
Kuhn, E., T. L. Wang, K. Doberstein, A. Bahadirli-Talbott, A. Ayhan, A. S. Sehdev, R. Drapkin, R. J. Kurman and I. M. ShihMod Pathol, 2016.
“Using reverse-phase protein arrays as pharmacodynamic assays for functional proteomics, biomarker discovery, and drug development in cancer.”
Lu, Y., S. Ling, A. M. Hegde, L. A. Byers, K. Coombes, G. B. Mills and R. AkbaniSemin Oncol, 2016.
“ERK and p38 MAPK Activities Determine Sensitivity to PI3K/mTOR Inhibition via Regulation of MYC and YAP.”
Muranen, T., L. M. Selfors, J. Hwang, L. L. Gallegos, J. L. Coloff, C. C. Thoreen, S. A. Kang, D. M. Sabatini, G. B. Mills and J. S. BruggeCancer Res, 2016.
“Enhancing the Cytotoxic Effects of PARP Inhibitors with DNA Demethylating Agents – A Potential Therapy for Cancer.”
Muvarak, N. E., K. Chowdhury, L. Xia, C. Robert, E. Y. Choi, Y. Cai, M. Bellani, Y. Zou, Z. N. Singh, V. H. Duong, T. Rutherford, P. Nagaria, S. M. Bentzen, M. M. Seidman, M. R. Baer, R. G. Lapidus, S. B. Baylin and F. V. RassoolCancer Cell, 2016.
“Antibody targeting facilitates effective intratumoral siRNA nanoparticle delivery to HER2-overexpressing cancer cells.”
Palanca-Wessels, M. C., G. C. Booth, A. J. Convertine, B. B. Lundy, G. Y. Berguig, M. F. Press, P. S. Stayton and O. W. PressOncotarget, 2016.
“Epigenetic remodeling regulates transcriptional changes between ovarian cancer and benign precursors.”
Elias, K. M., M. M. Emori, T. Westerling, H. Long, A. Budina-Kolomets, F. Li, E. MacDuffie, M. R. Davis, A. Holman, B. Lawney, M. L. Freedman, J. Quackenbush, M. Brown and R. DrapkinJCI Insight, 2016.
“Mutant p53 regulates ovarian cancer transformed phenotypes through autocrine matrix deposition.”
Iwanicki, M. P., H. Y. Chen, C. Iavarone, I. K. Zervantonakis, T. Muranen, M. Novak, T. A. Ince, R. Drapkin and J. S. BruggeJCI Insight, 2016.
“Pathogenesis and heterogeneity of ovarian cancer.”
Kroeger, P. T., Jr. and R. DrapkinCurr Opin Obstet Gynecol, 2016.
“It takes three to the DNA damage response tango.”
Schlam-Babayov, S., Y. Ziv and Y. ShilohMol Cell Oncol, 2021.
“Epigenetic Therapeutics: A New Weapon in the War Against Cancer.”
Ahuja, N., A. R. Sharma and S. B. BaylinAnnu Rev Med, 2016.
“Direct Upregulation of STAT3 by MicroRNA-551b-3p Deregulates Growth and Metastasis of Ovarian Cancer.”
Chaluvally-Raghavan, P., K. J. Jeong, S. Pradeep, A. M. Silva, S. Yu, W. Liu, T. Moss, C. Rodriguez-Aguayo, D. Zhang, P. Ram, J. Liu, Y. Lu, G. Lopez-Berestein, G. A. Calin, A. K. Sood and G. B. MillsCell Rep, 2016.