“let-7b and let-7c microRNAs promote histone H2B ubiquitylation and inhibit cell migration by targeting multiple components of the H2B deubiquitylation machinery.”Spolverini, A., G. Fuchs, D. R. Bublik and M. Oren Oncogene, 2017.
“RNF20 and histone H2B ubiquitylation exert opposing effects in Basal-Like versus luminal breast cancer.”Tarcic, O., R. Z. Granit, I. S. Pateras, H. Masury, B. Maly, Y. Zwang, Y. Yarden, V. G. Gorgoulis, E. Pikarsky, I. Ben-Porath and M. Oren Cell Death Differ, 2017.
“p53 is essential for DNA methylation homeostasis in naive embryonic stem cells, and its loss promotes clonal heterogeneity.”Tovy, A., A. Spiro, R. McCarthy, Z. Shipony, Y. Aylon, K. Alton, E. Ainbinder, N. Furth, A. Tanay, M. Barton and M. Oren Genes Dev, 2017.
“Imaging of hypoxia-inducible factor 1alpha and septin 9 interaction by bimolecular fluorescence complementation in live cancer cells.”Golan, M. and N. J. Mabjeesh Oncotarget, 2017.
“Coordinated Pulses of mRNA and of Protein Translation or Degradation Produce EGF-Induced Protein Bursts.”Golan-Lavi, R., C. Giacomelli, G. Fuks, A. Zeisel, J. Sonntag, S. Sinha, W. Kostler, S. Wiemann, U. Korf, Y. Yarden and E. Domany Cell Rep, 2017.
“Learning the Roles of the Hepatic Adaptive Immune System in Hepatocellular Carcinoma-Nature’s Guide for Successful Cancer Immunotherapy.”Heikenwalder, M. and E. Pikarsky Semin Liver Dis, 2017.
“Epigenetic Regulation of KPC1 Ubiquitin Ligase Effects the NF-kappaB Pathway in Melanoma.”Iida, Y., A. Ciechanover, D. M. Marzese, K. Hata, M. Bustos, S. Ono, J. Wang, M. P. Salomon, K. Tran, S. Lam, S. C. Hsu, N. Nelson, Y. Kravtsova-Ivantsiv, G. B. Mills, M. A. Davies and D. S. Hoon Clin Cancer Res, 2017.
“The Ubiquitin Code in the Ubiquitin-Proteasome System and Autophagy.”Kwon, Y. T. and A. Ciechanover Trends Biochem Sci, 2017.
“Cancer Cell-Autonomous Parainflammation Mimics Immune Cell Infiltration.”Lasry, A., D. Aran, A. J. Butte and Y. Ben-Neriah Cancer Res, 2017.
“Identification of UBact, a ubiquitin-like protein, along with other homologous components of a conjugation system and the proteasome in different gram-negative bacteria.”Lehmann, G., R. G. Udasin, I. Livneh and A. Ciechanover Biochem Biophys Res Commun, 2017.
“Monoubiquitination joins polyubiquitination as an esteemed proteasomal targeting signal.”Livneh, I., Y. Kravtsova-Ivantsiv, O. Braten, Y. T. Kwon and A. Ciechanover Bioessays, 2017.
“CK1alpha ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation.”Chang, C. H., C. J. Kuo, T. Ito, Y. Y. Su, S. T. Jiang, M. H. Chiu, Y. H. Lin, A. Nist, M. Mernberger, T. Stiewe, S. Ito, K. Wakamatsu, Y. A. Hsueh, S. Y. Shieh, I. Snir-Alkalay and Y. Ben-Neriah Proc Natl Acad Sci U S A, 2017.
“Stress-induced polyubiquitination of proteasomal ubiquitin receptors targets the proteolytic complex for autophagic degradation.”Cohen-Kaplan, V., A. Ciechanover and I. Livneh Autophagy, 2017.
“Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone.”Enuka, Y., M. E. Feldman, A. Chowdhury, S. Srivastava, M. Lindzen, A. Sas-Chen, R. Massart, D. Cheishvili, M. J. Suderman, Y. Zaltsman, C. A. Mazza, K. Shukla, C. Korner, N. Furth, M. Lauriola, M. Oren, S. Wiemann, M. Szyf and Y. Yarden Nucleic Acids Res, 2017.
“Immune defects caused by mutations in the ubiquitin system.”Etzioni, A., A. Ciechanover and E. Pikarsky J Allergy Clin Immunol, 2017.